Basic Research: Selected publications

Koivisto T, Vanninen R, Hurskainen H, Saari T, Hernesniemi J, Vapalahti M: Outcomes of ear-ly endovascular versus surgical treatment of ruptured cerebral aneurysms: A prospective ran-domized study. Stroke. 2000.

Frosen J, Piippo A, Paetau A, Kangasniemi M, Niemela M, Hernesniemi J, Jaaskelainen J: Remodeling of saccular cerebral artery aneurysm wall is associated with rupture: Histological analysis of 24 unruptured and 42 ruptured cases. Stroke. 2004.

Henkes H, Fischer S, Weber W, Miloslavski E, Felber S, Brew S, Kuehne D, Schackert G, Hernesniemi J, Niemela M, Kivipelto L, Koivisto T, Rinne J, Barrow D.L, Cullen S, Higashida R.T, Harrigan M.R, Hopkins L.N: Endovascular Coil Occlusion of 1811 Intracranial Aneurysms: Early Angiographic and Clinical Results. Neurosurgery. 2004.

Hoh B.L, Cheung A.C, Rabinov J.D, Pryor J.C, Carter B.S, Ogilvy C.S, Solomon R.A, Niemela M, Ishii K, Porras M, Hernesniemi J, Kobayashi S: Results of a prospective protocol of com-puted tomographic angiography in place of catheter angiography as the only diagnostic and pretreatment planning study for cerebral aneurysms by a combined neurovascular team. Neu-rosurgery. 2004.

Van Der Voet M, Olson J.M, Kuivaniemi H, Dudek D.M, Skunca M, Ronkainen A, Niemela M, Jaaskelainen J, Hernesniemi J, Helin K, Leinonen E, Biswas M, Tromp G: Intracranial Aneu-rysms in Finnish Families: Confirmation of Linkage and Refinement of the Interval to Chromo-some 19q13.3. American Journal of Human Genetics. 2004.

Helgadottir A, Thorleifsson G, Magnusson K.P, Gretarsdottir S, Steinthorsdottir V, Manolescu A, Jones G.T, Rinkel G.J.E, Blankensteijn J.D, Ronkainen A, Jaaskelainen J.E, Kyo Y, Lenk G.M, Sakalihasan N, Kostulas K, Gottsater A, Flex A, Stefansson H, Hansen T, Andersen G, Weinsheimer S, Borch-Johnsen K, Jorgensen T, Shah S.H, Quyyumi A.A, Granger C.B, Reilly M.P, Austin H, Levey A.I, Vaccarino V, Palsdottir E, Walters G.B, Jonsdottir T, Snorradottir S, Magnusdottir D, Gudmundsson G, Ferrell R.E, Sveinbjornsdottir S, Hernesniemi J, Niemela M, Limet R, Andersen K, Sigurdsson G, Benediktsson R, Verhoeven E.L.G, Teijink J.A.W, Grob-bee D.E, Rader D.J, Collier D.A, Pedersen O, Pola R, Hillert J, Lindblad B, Valdimarsson E.M, Magnadottir H.B, Wijmenga C, Tromp G, Baas A.F, Ruigrok Y.M, Van Rij A.M, Kuivaniemi H, Powell J.T, Matthiasson S.E, Gulcher J.R, Thorgeirsson G, Kong A, Thorsteinsdottir U, Ste-fansson K: The same sequence variant on 9p21 associates with myocardial infarction, ab-dominal aortic aneurysm and intracranial aneurysm. Nature Genetics. 2008.

Bilguvar K, Yasuno K, Niemela M, Ruigrok Y.M, Von Und Zu Fraunberg M, Van Duijn C.M, Van Den Berg L.H, Mane S, Mason C.E, Choi M, Gaal E, Bayri Y, Kolb L, Arlier Z, Ravuri S, Ronkainen A, Tajima A, Laakso A, Hata A, Kasuya H, Koivisto T, Rinne J, Ohman J, Breteler M.M.B, Wijmenga C, State M.W, Rinkel G.J.E, Hernesniemi J, Jaaskelainen J.E, Palotie A, In-oue I, Lifton R.P, Gunel M: Susceptibility loci for intracranial aneurysm in European and Japa-nese populations. Nature Genetics. 2008.

Yasuno K, Bilguvar K, Bijlenga P, Low S.-K, Krischek B, Auburger G, Simon M, Krex D, Arlier Z, Nayak N, Ruigrok Y.M, Niemela M, Tajima A, Von Und Zu Fraunberg M, Doczi T, Wirjatijasa F, Hata A, Blasco J, Oszvald A, Kasuya H, Zilani G, Schoch B, Singh P, Stuer C, Risselada R, Beck J, Sola T, Ricciardi F, Aromaa A, Illig T, Schreiber S, Van Duijn C.M, Van Den Berg L.H, Perret C, Proust C, Roder C, Ozturk A.K, Gaal E, Berg D, Geisen C, Friedrich C.M, Summers P, Frangi A.F, State M.W, Wichmann H.E, Breteler M.M.B, Wijmenga C, Mane S, Peltonen L, Elio V, Sturkenboom M.C.J.M, Lawford P, Byrne J, MacHo J, Sandalcioglu E.I, Meyer B, Raabe A, Steinmetz H, Rufenacht D, Jaaskelainen J.E, Hernesniemi J, Rinkel G.J.E, Zem-butsu H, Inoue I, Palotie A, Cambien F, Nakamura Y, Lifton R.P, Gunel M: Genome-wide as-sociation study of intracranial aneurysm identifies three new risk loci. Nature Genetics. 2010.

Korja M, Silventoinen K, McCarron P, Zdravkovic S, Skytthe A, Haapanen A, de Faire U, Pedersen NL, Christensen K, Koskenvuo M, Kaprio J; GenomEUtwin Project: Genetic epide-miology of spontaneous subarachnoid hemorrhage: Nordic Twin Study. Stroke 2010.

Gaál EI, Salo P, Kristiansson K, Rehnström K, Kettunen J, Sarin AP, Niemelä M, Jula A, Rai-takari OT, Lehtimäki T, Eriksson JG, Widen E, Günel M, Kurki M, von und Zu Fraunberg M, Jääskeläinen JE, Hernesniemi J, Järvelin MR, Pouta A; International Consortium for Blood Pressure Genome-Wide Association Studies, Newton-Cheh C, Salomaa V, Palotie A, Perola M: Intracranial aneurysm risk locus 5q23.2 is associated with elevated systolic blood pressure. Plos Genetics 2012.