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Medicine safety information for mothers – Teratological information service

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We provide information on medications and other external factors that have an adverse impact on fertility, pregnancy and fetal development. We also advise you on all medication issues during breastfeeding. You can contact us when you are only just planning the pregnancy.

We make no comment on how the mother, the pregnancy, or the child are cared for, and we do not prescribe medications. When the service is not open, please contact your local maternity clinic. If you want to talk about exposure and risks at work, please contact your occupational health care service in the first instance.

We can also be contacted by health care professionals, pharmacies, the authorities, and the media. Health care professionals may also contact us with patient-related queries by e-mail at: konsultaatiot.teratologinen@hus.fi. We do not respond to questions sent by the general public by e-mail.

If you cannot find an answer to your question here, please contact us either by phone or via the chat

News: Nonsteroidal anti-inflammatory drugs (NSAIDs)

Remember that the use of anti-inflammatory drugs should be avoided already from the 20th week of pregnancy. In their assessments, the European Medicines Agency (EMA) and the US Food and Drug Administration (FDA) recommend avoiding the use of NSAIDs from 20 weeks of pregnancy onwards.

Their use should be limited to situations where there are no safer alternatives, the dose should be the lowest possible, and the length of use should be restricted to a maximum of two days (EMA 2022; FDA 2020). Possible longer-term use should be discussed with the attending physician, and in such a situation, the physician must assess the risks and the need to monitor the pregnancy.

Repetitive use of NSAIDs from these weeks onwards can adversely affect the fetal renal function and the blood supply to the heart of the fetus. The danger of harm to the fetus is emphasized as the pregnancy progresses, and from 28 weeks of pregnancy, repeated use of NSAIDs is contraindicated. Paracetamol is the preferred choice if an analgesic is needed.

Matters to note while pregnant or breastfeeding

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